Dear Advances in Pulmonary Hypertension readers:
Pulmonary arterial hypertension (PAH) patients often ask, "How long do I have?" after being diagnosed with PAH. The question is difficult to answer precisely as prognostication is complex and outcomes seem to be improving with the advent of PAH-specific therapy. The current issue ofAdvances reviews the current state of affairs as well as future opportunities to further refine the clinical assessment of PAH severity to enable a more individualized prognosis. There has been significant progress with prognostic risk scoring and cardiac imaging as well as active research on the role of biomarkers, all of which are potentially useful to clinicians to help better answer the patients' question about the future course of their disease.
—Charles D. Burger, MD, Editor-in-Chief